Mgr. Lenka Radová, Ph.D.

2017

• BENCUROVA, P; BALOUN, J; MUSILOVA, K; RADOVA, L; TICHY, B; PAIL, M; ZEMAN, M; BRICHTOVA, E; HERMANOVA, M; POSPISILOVA, S; MRAZ, M; BRAZDIL, M, 2017:MicroRNA and mesial temporal lobe epilepsy with hippocampal sclerosis: Whole miRNome profiling of human hippocampus. EPILEPSIA 58 (10), p. 1782 - 1793.
• KANTOROVA, B; MALCIKOVA, J; BRAZDILOVA, K; BORSKY, M; PLEVOVA, K; SMARDOVA, J; RADOVA, L; TOM, N; TRBUSEK, M; DIVISKOVA, E; FRANCOVA, HS; NAVRKALOVA, V; DOUBEK, M; BRYCHTOVA, Y; MAYER, J; POSPISILOVA, S, 2017:Single cell analysis revealed a coexistence of NOTCH1 and TP53 mutations within the same cancer cells in chronic lymphocytic leukaemia patients. BRITISH JOURNAL OF HAEMATOLOGY 178 (6), p. 979 - 982.

2016

• HERNANDEZ-SANCHEZ, M; RADOVA, L; KOTASKOVA, J; TAMBORERO, D; RODRIGUEZ, AE; PLEVOVA, K; ABAIGAR, M; BIKOS, V; BENITO, R; TAKACOVA, S; QUIJADA, M; MARTIN, AA; ALCOCEBA, M; DE COCA, AG; DOUBEK, M; GONZALEZ, M; LOPEZ-BIGAS, N; POSPISILOVA, S; HERNANDEZ-RIVAS, JM, 2016:Analysis of Clonal Evolution in Chronic Lymphocytic Leukemia from Inactive to Symptomatic Disease Prior Treatment Using Whole-Exome Sequencing. BLOOD 128 (22)
• KRYUKOV, F; NEMEC, P; RADOVA, L; KRYUKOVA, E; OKUBOTE, S; MINARIK, J; STEFANIKOVA, Z; POUR, L; HAJEK, R, 2016:Centrosome associated genes pattern for risk sub-stratification in multiple myeloma. JOURNAL OF TRANSLATIONAL MEDICINE 14
• KUBESOVA, B; PAVLOVA, S; MALCIKOVA, J; KABATHOVA, J; RADOVA, L; TOM, N; TICHY, B; PLEVOVA, K; KANTOROVA, B; FIEDOROVA, K; KISSOVA, J; GISSLINGER, B; GISSLINGER, H; MAYER, J; KRALOVICS, R; POSPISILOVA, S; DOUBEK, M, 2016:Low-Burden TP53 Mutations Occur in Chronic Phase of Myeloproliferative Neoplasms Regardless of Hydroxyurea Administration, Disease Type, and JAK2 Status. BLOOD 128 (22)
• MELAZZINI, F; PALOMBO, F; BALDUINI, A; DE ROCCO, D; MARCONI, C; NORIS, P; GNAN, C; PIPPUCCI, T; BOZZI, V; FALESCHINI, M; BAROZZI, S; DOUBEK, M; DI BUDUO, CA; KOZUBIK, KS; RADOVA, L; LOFFREDO, G; POSPISILOVA, S; ALFANO, C; SERI, M; BALDUINI, CL; PECCI, A; SAVOIA, A, 2016:Clinical and pathogenic features of ETV6-related thrombocytopenia with predisposition to acute lymphoblastic leukemia. HAEMATOLOGICA 101 (11), p. 1333 - 1342.
• MLCOCHOVA, H; MACHACKOVA, T; RABIEN, A; RADOVA, L; FABIAN, P; ILIEV, R; SLABA, K; POPRACH, A; KILIC, E; STANIK, M; REDOVA-LOJOVA, M; SVOBODA, M; DOLEZEL, J; VYZULA, R; JUNG, K; SLABY, O, 2016:Epithelial-mesenchymal transition-associated microRNA/mRNA signature is linked to metastasis and prognosis in clear-cell renal cell carcinoma. SCIENTIFIC REPORTS 6
• NAVRKALOVA, V; YOUNG, E; BALIAKAS, P; RADOVA, L; SUTTON, LA; PLEVOVA, K; MANSOURI, L; LJUNGSTROM, V; NTOUFA, S; DAVIS, Z; JULIUSSON, G; SMEDBY, KE; BELESSI, C; PANAGIOTIDIS, P; TOULOUMENIDOU, T; DAVI, F; LANGERAK, AW; GHIA, P; STREFFORD, JC; OSCIER, D; MAYER, J; STAMATOPOULOS, K; POSPISILOVA, S; ROSENQUIST, R; TRBUSEK, M, 2016:ATM mutations in major stereotyped subsets of chronic lymphocytic leukemia: enrichment in subset #2 is associated with markedly short telomeres. HAEMATOLOGICA 101 (9)
• POPPOVA, L; JANOVSKA, P; PLEVOVA, K; RADOVA, L; PLESINGEROVA, H; BORSKY, M; KOTASKOVA, J; KANTOROVA, B; HLOZKOVA, M; FIGULOVA, J; BRYCHTOVA, Y; DOUBEK, M; KOZUBIK, A; POSPISILOVA, S; PAVLOVA, S; BRYJA, V, 2016:DECREASED EXPRESSION OF WNT3, A CANONICAL WNT PATHWAY LIGAND, IS FREQUENT IN CHRONIC LYMPHOCYTIC LEUKEMIA PROGRESSION AND IDENTIFIES PATIENTS WITH SHORT TREATMENT-FREE SURVIVAL IN MUTATED IGHV SUBSET. HAEMATOLOGICA 101 , p. 423 - 424.
• POPPOVA, L; JANOVSKA, P; PLEVOVA, K; RADOVA, L; PLESINGEROVA, H; BORSKY, M; KOTASKOVA, J; KANTOROVA, B; HLOZKOVA, M; FIGULOVA, J; BRYCHTOVA, Y; MACHALOVA, M; URIK, M; DOUBEK, M; KOZUBIK, A; POSPISILOVA, S; PAVLOVA, S; BRYJA, V, 2016:Decreased WNT3 expression in chronic lymphocytic leukaemia is a hallmark of disease progression and identifies patients with worse prognosis in the subgroup with mutated IGHV. BRITISH JOURNAL OF HAEMATOLOGY 175 (5), p. 851 - 859.
• SEDLARIKOVA, L; GROMESOVA, B; KUBACZKOVA, V; RADOVA, L; ALMASI, M; PENKA, M; ADAM, Z; POUR, L; KREJCI, M; SEVCIKOVA, S; HAJEK, R, 2016:LONG NON-CODING RNAS IN MULTIPLE MYELOMA. HAEMATOLOGICA 101 , p. 518 - 518.
• VYCHYTILOVA-FALTEJSKOVA, P; RADOVA, L; SACHLOVA, M; KOSAROVA, Z; SLABA, K; FABIAN, P; GROLICH, T; PROCHAZKA, V; KALA, Z; SVOBODA, M; KISS, I; VYZULA, R; SLABY, O, 2016:Serum-based microRNA signatures in early diagnosis and prognosis prediction of colon cancer. CARCINOGENESIS 37 (10), p. 941 - 950.
• ZAPRAZNA, K; MALCIKOVA, J; TOM, N; RADOVA, L; TRBUSEK, M; ATCHISON, M; POSPISILOVA, S, 2016:ACTIVATION INDUCED DEAMINASE SPLICE VARIANTS EXPRESSED IN B CELL LEUKEMIA AND LYMPHOMA DO NOT RETAIN THEIR CATALYTIC ACTIVITY. HAEMATOLOGICA 101 , p. 429 - 430.

2015

• BESSE, L; SEDLARIKOVA, L; KRYUKOV, F; NEKVINDOVA, J; RADOVA, L; SLABY, O; KUGLIK, P; ALMASI, M; PENKA, M; KREJCI, M; ADAM, Z; POUR, L; SEVCIKOVA, S; HAJEK, R, 2015:Circulating Serum MicroRNA-130a as a Novel Putative Marker of Extramedullary Myeloma. PLOS ONE 10 (9)
• KRYUKOV, F; NEMEC, P; RADOVA, L; KRYUKOVA, E; KUFOVA, Z; SEDLARIKOVA, L; SEVCIKOVA, S; HAJEK, R, 2015:CENTROSOME ASSOCIATED GENES PATTERN FOR RISK SUBSTRATIFICATION IN MULTIPLE MYELOMA. HAEMATOLOGICA 100 , p. 247 - 247.
• MALCIKOVA, J; STANO-KOZUBIK, K; TICHY, B; KANTOROVA, B; PAVLOVA, S; TOM, N; RADOVA, L; SMARDOVA, J; PARDY, F; DOUBEK, M; BRYCHTOVA, Y; MRAZ, M; PLEVOVA, K; DIVISKOVA, E; OLTOVA, A; MAYER, J; POSPISILOVA, S; TRBUSEK, M, 2015:Detailed analysis of therapy-driven clonal evolution of TP53 mutations in chronic lymphocytic leukemia. LEUKEMIA 29 (4), p. 877 - 885.
• MLCOCHOVA, J; FALTEJSKOVA-VYCHYTILOVA, P; FERRACIN, M; ZAGATTI, B; RADOVA, L; SVOBODA, M; NEMECEK, R; JOHN, S; KISS, I; VYZULA, R; NEGRINI, M; SLABY, O, 2015:MicroRNA expression profiling identifies miR-31-5p/3p as associated with time to progression in wild-type RAS metastatic colorectal cancer treated with cetuximab. ONCOTARGET 6 (36), p. 38695 - 38704.
• NAVRKALOVA, V; YOUNG, E; BALIAKAS, P; RADOVA, L; PLEVOVA, K; SUTTON, LA; MANSOURI, L; LJUNGSTROM, V; NTOUFA, S; DAVIS, Z; JULIUSSON, G; SMEDBY, KE; BELESSI, C; PANAGIOTIDIS, P; DAVI, F; LANGERAK, AW; GHIA, P; STREFFORD, JC; OSCIER, DG; STAMATOPOULOS, K; POSPISILOVA, S; ROSENQUIST, R; TRBUSEK, M, 2015:ATM Mutations in Major Stereotyped CLL Subsets: Enrichment in Subset #2 is Associated with Unfavourable Outcome. BLOOD 126 (23)
• TOM, N; MALCIKOVA, J; RADOVA, L; KANTOROVA, B; PARDY, F; PAVLOVA, S; PAL, K; MRAZ, M; TICHY, B; DOUBEK, M; BRYCHTOVA, Y; PLEVOVA, K; MAYER, J; TRBUSEK, M; POSPISILOVA, S, 2015:MUTATIONS IN THE TP53 GENE SHOW FEATURES OF SOMATIC HYPERMUTATION PROCESS WITH PROMINENT DIFFERENCE BETWEEN IGHV MUTATED AND UNMUTATED CHRONIC LYMPHOCYTIC LEUKEMIA. HAEMATOLOGICA 100 , p. 224 - 225.