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Pokročilé nano a mikrotechnologie Pokročilé materiály Strukturní biologie Gen. a prot. rostlin. systémů Molekulární medicína Výzkum mozku a lidské mysli Molekulární vet. medicína

Mgr. Pavel Plevka, Ph.D.

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Mgr. Pavel Plevka, Ph.D.
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Telefon: +420 54949 7756
Výzkumná skupina: Strukturní virologie - Pavel Plevka
Researcher ID

Pavel Plevka is research group leader at Central European Institute of Technology, Masaryk University. He obtained his MSc. degree in molecular biology and virology from Charles University and his Ph.D. in structural biology from Uppsala University in 2009. From 2009 till 2013 he was a post-doctoral fellow with Michael Rossmann at Purdue University. In 2013 he established the group of Structural Virology at CEITEC, Masaryk University.

Plevka has determined structures of several viruses, most notably that of human enterovirus 71 that causes potentially fatal encephalitis in small children. Furthermore, he studied maturation of dengue virus. He focuses on X-ray crystallography and cryo-electron microscopy of viruses and other macromolecular complexes.

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2017

  • JASNOVIDOVA, O; KLUMPLER, T; KUBICEK, K; KALYNYCH, S; PLEVKA, P; STEFL, R, 2017:Structure and dynamics of the RNAPII CTDsome with Rtt103. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 114 (42), p. 11133 - 11138.
  • SKUBNIK, K; NOVACEK, J; FUZIK, T; PRIDAL, A; PAXTON, RJ; PLEVKA, P, 2017:Structure of deformed wing virus, a major honey bee pathogen. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 114 (12), p. 3210 - 3215.
  • SPURNY, R; PRIDAL, A; PALKOVE, L; TRAN KIEM, H. K; DE MIRANDA, J R; PLEVKA,, 2017:Virion structure of black queen cell virus, a common honeybee pathogen. JOURNAL OF VIROLOGY

2016

  • KALYNYCH S; PŘIDAL A; PÁLKOVÁ L; LEVDANSKY Y; DE MIRANDA JR; PLEVKA P, 2016:Virion structure of iflavirus slow bee paralysis virus at 2.6Å resolution. JOURNAL OF VIROLOGY 90 (16), p. 7444 - 7455.
  • KALYNYCH, S; PALKOVA, L; PLEVKA, P, 2016:The Structure of Human Parechovirus 1 Reveals an Association of the RNA Genome with the Capsid. JOURNAL OF VIROLOGY 90 (3), p. 1377 - 1386.
  • KALYNYCH, S; PRIDAL, A; PALKOVA, L; LEVDANSKY, Y; DE MIRANDA, JR; PLEVKA, P, 2016:Virion Structure of Iflavirus Slow Bee Paralysis Virus at 2.6-Angstrom Resolution. JOURNAL OF VIROLOGY 90 (16), p. 7444 - 7455.
  • MULLAPUDI E; NOVÁČEK J; PÁLKOVÁ L; KULICH P; LINDBERG AM; VAN KUPPEVELD FJ; PLEVKA P, 2016:Structure and genome release mechanism of human cardiovirus Saffold virus-3. JOURNAL OF VIROLOGY , p. [Epub ahead of print] - .
  • MULLAPUDI E; PŘIDAL A; PÁLKOVÁ L; DE MIRANDA JR; PLEVKA P, 2016:Virion structure of Israeli acute bee paralysis virus. JOURNAL OF VIROLOGY 90 (18), p. 8150 - 8159.
  • MULLAPUDI, E; NOVACEK, J; PALKOVA, L; KULICH, P; LINDBERG, AM; VAN KUPPEVELD, FJM; PLEVKA, P, 2016:Structure and Genome Release Mechanism of the Human Cardiovirus Saffold Virus 3. JOURNAL OF VIROLOGY 90 (17), p. 7628 - 7639.
  • NOVÁČEK J; ŠIBOROVÁ M; BENEŠÍK M; PANTŮČEK R; DOŠKAŘ J; PLEVKA P, 2016:Structure and genome release of Twort-like Myoviridae phage with a double-layered baseplate. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 113 (33), p. 9351 - 6.
  • SABIN, C; FUZIK, T; SKUBNIK, K; PALKOVA, L; LINDBERG, AM; PLEVKA, P, 2016:Structure of Aichi Virus 1 and Its Empty Particle: Clues to Kobuvirus Genome Release Mechanism. JOURNAL OF VIROLOGY 90 (23), p. 10800 - 10810.
  • SABIN, C; PLEVKA, P, 2016:The use of noncrystallographic symmetry averaging to solve structures from data affected by perfect hemihedral twinning. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS 72 , p. 188 - 197.

2013

  • MENG, G; ZHANG, XZ; PLEVKA, P; YU, Q; TIJSSEN, P; ROSSMANN, MG, 2013:The Structure and Host Entry of an Invertebrate Parvovirus. JOURNAL OF VIROLOGY 87 (23), p. 12523 - 12530.
  • PRASAD, VM; WILLOWS, SD; FOKINE, A; BATTISTI, AJ; SUN, SY; PLEVKA, P; HOBMAN, TC; ROSSMANN, MG, 2013:Rubella virus capsid protein structure and its role in virus assembly and infection. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 110 (50), p. 20105 - 20110.
  • WANG, ZQ; LI, L; PENNINGTON, JG; SHENG, J; YAP, ML; PLEVKA, P; MENG, G; SUN, L; JIANG, W; ROSSMANN, MG, 2013:Obstruction of Dengue Virus Maturation by Fab Fragments of the 2H2 Antibody. JOURNAL OF VIROLOGY 87 (16), p. 8909 - 8915.
  • ZHANG, XZ; SHENG, J; PLEVKA, P; KUHN, RJ; DIAMOND, MS; ROSSMANN, MG, 2013:Dengue structure differs at the temperatures of its human and mosquito hosts. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 110 (17), p. 6795 - 6799.

2012

  • BATTISTI, AJ; MENG, G; WINKLER, DC; MCGINNES, LW; PLEVKA, P; STEVEN, AC; MORRISON, TG; ROSSMANN, MG, 2012:Structure and assembly of a paramyxovirus matrix protein. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 109 (35), p. 13996 - 14000.
  • BATTISTI, AJ; YODER, JD; PLEVKA, P; WINKLER, DC; PRASAD, VM; KUHN, RJ; FREY, TK; STEVEN, AC; ROSSMANN, MG, 2012:Cryo-Electron Tomography of Rubella Virus. JOURNAL OF VIROLOGY 86 (20), p. 11078 - 11085.
  • PLEVKA, P; BATTISTI, AJ; WINKLER, DC; TARS, K; HOLDAWAY, HA; BATOR, CM; ROSSMANN, MG, 2012:Sample Preparation Induced Artifacts in Cryo-Electron Tomographs. MICROSCOPY AND MICROANALYSIS 18 (5), p. 1043 - 1048.
  • PLEVKA, P; PERERA, R; CARDOSA, J; KUHN, RJ; ROSSMANN, MG, 2012:Crystal Structure of Human Enterovirus 71. SCIENCE 336 (6086), p. 1274 - 1274.
  • PLEVKA, P; PERERA, R; CARDOSA, J; KUHN, RJ; ROSSMANN, MG, 2012:Structure determination of enterovirus 71. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 68 , p. 1217 - 1222.

2011

  • KAUFMANN, B; EL-FAR, M; PLEVKA, P; BOWMAN, VD; LI, Y; TIJSSEN, P; ROSSMANN, MG, 2011:Structure of Bombyx mori Densovirus 1, a Silkworm Pathogen. JOURNAL OF VIROLOGY 85 (10), p. 4691 - 4697.
  • ROSSMANN, MG; BATTISTI, AJ; PLEVKA, P, 2011:FUTURE PROSPECTS. ADVANCES IN PROTEIN CHEMISTRY AND STRUCTURAL BIOLOGY, VOL 82: RECENT ADVANCES IN ELECTRON CRYOMICROSCOPY, PT B 82 , p. 101 - 121.

2010

  • KAUFMANN, B; PLEVKA, P; KUHN, RJ; ROSSMANN, MG, 2010:Crystallization and preliminary X-ray diffraction analysis of West Nile virus. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS 66 , p. 558 - 562.
  • PLEVKA, P; HAFENSTEIN, S; HARRIS, KG; CIFUENTE, JO; ZHANG, Y; BOWMAN, VD; CHIPMAN, PR; BATOR, CM; LIN, F; MEDOF, ME; ROSSMANN, MG, 2010:Interaction of Decay-Accelerating Factor with Echovirus 7. JOURNAL OF VIROLOGY 84 (24), p. 12665 - 12674.
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