prof. MUDr. Jiří Mayer, CSc.

2017

• KANTOROVA, B; MALCIKOVA, J; BRAZDILOVA, K; BORSKY, M; PLEVOVA, K; SMARDOVA, J; RADOVA, L; TOM, N; TRBUSEK, M; DIVISKOVA, E; FRANCOVA, HS; NAVRKALOVA, V; DOUBEK, M; BRYCHTOVA, Y; MAYER, J; POSPISILOVA, S, 2017:Single cell analysis revealed a coexistence of NOTCH1 and TP53 mutations within the same cancer cells in chronic lymphocytic leukaemia patients. BRITISH JOURNAL OF HAEMATOLOGY 178 (6), p. 979 - 982.
• LEDEREROVA, A; KOZLOVA, V; VAKULOVA, V; DOUBEK, M; MAYER, J; POSPISILOVA, S; SMIDA, M, 2017:B CELLS RESISTANT TO CD20 MONOCLONAL ANTIBODIES DISPLAY SPECIFIC ALTERATIONS IN GENE EXPRESSION PROFILE. HAEMATOLOGICA 102 , p. 709 - 709.
• PAVLASOVA, G; BORSKY, M; SVOBODOVA, V; MUSILOVA, K; CERNA, K; SEDA, V; OSICKOVA, J; BRYCHTOVA, Y; DOUBEK, M; POSPISILOVA, S; MAYER, J; MRAZ, M, 2017:BCR SIGNALLING PROFICIENT CHRONIC LYMPHOCYTIC LEUKAEMIA B CELLS ARE PRONE TO RITUXIMAB MEDIATED ELIMINATION IN VIVO. HAEMATOLOGICA 102 , p. 412 - 412.

2016

• BEZDICEK, M; LENGEROVA, M; RICNA, D; WEINBERGEROVA, B; KOCMANOVA, I; VOLFOVA, P; DRGONA, L; POCZOVA, M; MAYER, J; RACIL, Z, 2016:Rapid detection of fungal pathogens in bronchoalveolar lavage samples using panfungal PCR combined with high resolution melting analysis. MEDICAL MYCOLOGY 54 (7), p. 714 - 724.
• CORTES, JE; SAGLIO, G; KANTARJIAN, HM; BACCARANI, M; MAYER, J; BOQUE, C; SHAH, NP; CHUAH, C; CASANOVA, L; BRADLEY-GARELIK, B; MANOS, G; HOCHHAUS, A, 2016:Final 5-Year Study Results of DASISION: The Dasatinib Versus Imatinib Study in Treatment-Naive Chronic Myeloid Leukemia Patients Trial. JOURNAL OF CLINICAL ONCOLOGY 34 (20), p. 2333 - U54.
• CULEN, M; BORSKY, M; NEMETHOVA, V; RAZGA, F; SMEJKAL, J; JURCEK, T; DVORAKOVA, D; ZACKOVA, D; WEINBERGEROVA, B; SEMERAD, L; SADOVNIK, I; EISENWORT, G; HERRMANN, H; VALENT, P; MAYER, J; RACIL, Z, 2016:Quantitative assessment of the CD26+leukemic stem cell compartment in chronic myeloid leukemia: Patient-subgroups, prognostic impact, and technical aspects. ONCOTARGET 7 (22), p. 33016 - 33024.
• GREIL, R; OBRTLIKOVA, P; SMOLEJ, L; KOZAK, T; STEURER, M; ANDEL, J; BURGSTALLER, S; MIKUSKOVA, E; GERCHEVA, L; NOSSLINGER, T; PAPAJIK, T; LADICKA, M; GIRSCHIKOFSKY, M; HRUBISKO, M; JAGER, U; FRIDRIK, M; PECHERSTORFER, M; KRALIKOVA, E; BURCOVEANU, C; SPASOV, E; PETZER, A; MIHAYLOV, G; RAYNOV, J; OEXLE, H; ZABERNIGG, A; FLOCHOVA, E; PALASTHY, S; STEHLIKOVA, O; DOUBEK, M; ALTENHOFER, P; PLEYER, L; MELCHARDT, T; KLINGLER, A; MAYER, J; EGLE, A, 2016:Rituximab maintenance versus observation alone in patients with chronic lymphocytic leukaemia who respond to first-line or second-line rituximab-containing chemoimmunotherapy: final results of the AGMT CLL-8a Mabtenance randomised trial. LANCET HAEMATOLOGY 3 (7), p. E317 - E329.
• HO, AD; SCHETELIG, J; BOCHTLER, T; SCHAICH, M; SCHAFER-ECKART, K; HANEL, M; ROSLER, W; EINSELE, H; KAUFMANN, M; SERVE, H; BERDE, WE; STELLJES, M; MAYER, J; REICHLE, A; BALDUS, CD; SCHMITZ, N; KRAMER, M; ROLLIG, C; BORNHAUSER, M; THIEDE, C; EHNINGER, G, 2016:Allogeneic Stem Cell Transplantation Improves Survival in Patients with Acute Myeloid Leukemia Characterized by a High Allelic Ratio of Mutant FLT3-ITD. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION 22 (3), p. 462 - 469.
• KUBESOVA, B; PAVLOVA, S; MALCIKOVA, J; KABATHOVA, J; RADOVA, L; TOM, N; TICHY, B; PLEVOVA, K; KANTOROVA, B; FIEDOROVA, K; KISSOVA, J; GISSLINGER, B; GISSLINGER, H; MAYER, J; KRALOVICS, R; POSPISILOVA, S; DOUBEK, M, 2016:Low-Burden TP53 Mutations Occur in Chronic Phase of Myeloproliferative Neoplasms Regardless of Hydroxyurea Administration, Disease Type, and JAK2 Status. BLOOD 128 (22)
• SMIDA, M; KOZLOVA, V; VAKULOVA, V; LEDEREROVA, A; DOUBEK, M; MAYER, J; POSPISILOVA, S, 2016:Cellular Mechanisms Regulating CD20 As a Target of Monoclonal Antibody Therapy in B-Lymphoid Malignancies. BLOOD 128 (22)

2015

• BRAZDILOVA, K; PLEVOVA, K; FRANCOVA, HS; KOCKOVA, H; CHMELIKOVA, M; BORSKY, M; BURCKOVA, K; KANTOROVA, B; TICHY, B; SKABRAHOVA, H; BRYCHTOVA, Y; MAYER, J; DOUBEK, M; POSPISILOVA, S, 2015:Single Cell Analysis of IG Genes in CLL: Cases with Multiple IGH Rearrangements Are Constituted of Several Independent Clones Even When Indistinguishable By Flow Cytometry. BLOOD 126 (23)
• JASKOVA, Z; MALCIKOVA, J; SMARDOVA, J; BRYCHTOVA, Y; MAYER, J; TRBUSEK, M, 2015:ELIMINATION OF MUTATED P53 PROTEIN AND INDUCTION OF P53 DOWNSTREAM GENES IN CHRONIC LYMPHOCYTIC LEUKEMIA CELLS USING PRIMA-1MET. HAEMATOLOGICA 100 , p. 414 - 414.
• KANTOROVA, B; MALCIKOVA, J; BRAZDILOVA, K; BORSKY, M; PLEVOVA, K; SMARDOVA, J; TRBUSEK, M; BRYCHTOVA, Y; DOUBEK, M; MAYER, J; POSPISILOVA, S, 2015:Single Cell Analysis Proves the Coexistence of NOTCH1 and TP53 Mutations within the Same Cancer Cells in Patients with Chronic Lymphocytic Leukemia. BLOOD 126 (23)
• KOTASKOVA, J; MALCIKOVA, J; DIVISKOVA, E; PAVLOVA, S; MEJSTRIKOVA, S; VRANOVA, V; PLEVOVA, K; PLESINGEROVA, H; DOUBEK, M; MAYER, J; POSPISILOVA, S, 2015:13Q DELETION IS PREDOMINANT CYTOGENETIC ABERRATION NEWLY AQUIRED DURING CHRONIC LYMPHOCYTIC LEUKEMIA COURSE IRRESPECTIVE OF DISEASE ACTIVITY AND TREATMENT STATUS. HAEMATOLOGICA 100 , p. 417 - 418.
• MALCIKOVA, J; STANO-KOZUBIK, K; TICHY, B; KANTOROVA, B; PAVLOVA, S; TOM, N; RADOVA, L; SMARDOVA, J; PARDY, F; DOUBEK, M; BRYCHTOVA, Y; MRAZ, M; PLEVOVA, K; DIVISKOVA, E; OLTOVA, A; MAYER, J; POSPISILOVA, S; TRBUSEK, M, 2015:Detailed analysis of therapy-driven clonal evolution of TP53 mutations in chronic lymphocytic leukemia. LEUKEMIA 29 (4), p. 877 - 885.
• PAVLASOVA, G; SEDA, V; BORSKY, M; CERNA, K; OSICKOVA, J; MAYER, J; POSPISILOVA, S; DAVIDS, MS; BROWN, JR; MRAZ, M, 2015:Microenvironmental Interactions up-Regulate CD20 Expression in CLL B Cells through the CXCR4/SDF-1 Axis: Implications for CD20-Targeting Antibodies and the Use of BCR-Inhibitors in Combination. BLOOD 126 (23)
• TOM, N; MALCIKOVA, J; RADOVA, L; KANTOROVA, B; PARDY, F; PAVLOVA, S; PAL, K; MRAZ, M; TICHY, B; DOUBEK, M; BRYCHTOVA, Y; PLEVOVA, K; MAYER, J; TRBUSEK, M; POSPISILOVA, S, 2015:MUTATIONS IN THE TP53 GENE SHOW FEATURES OF SOMATIC HYPERMUTATION PROCESS WITH PROMINENT DIFFERENCE BETWEEN IGHV MUTATED AND UNMUTATED CHRONIC LYMPHOCYTIC LEUKEMIA. HAEMATOLOGICA 100 , p. 224 - 225.
• ZEMANOVA, J; PARUCH, K; KREJCI, L; SOUCEK, K; HYLSE, O; BOUDNY, M; BORSKY, M; OSICKOVA, J; KHIRSARIYA, P; SEBEJOVA, L; NAVRKALOVA, V; MALCIKOVA, J; DIVISKOVA, E; BRYCHTOVA, Y; MAYER, J; TRBUSEK, M, 2015:CHRONIC LYMPHOCYTIC LEUKEMIA CELLS ARE HIGHLY SUSCEPTIBLE TO DIRECT INHIBITION OF CHECKPOINT KINASE 1. HAEMATOLOGICA 100 , p. 417 - 417.

2014

• DOUBEK, M; SROVNAL, J; PLEVOVA, K; TRIZULJAK, J; BRYCHTOVA, Y; SEMERAD, L; LETALOVA, E; BENEDIKOVA, A; MAYER, J; HAJDUCH, M; POSPISILOVA, S, 2014:ANALYSIS OF MERKEL CELL POLYOMAVIRUS PROGNOSTIC SIGNIFICANCE IN CHRONIC LYMPHOCYTIC LEUKEMIA. HAEMATOLOGICA 99 , p. 325 - 325.
• HOFFMANN, V; LINDOERFER, D; THALER, J; LABAR, B; MELANTHIOU, F; MAYER, J; EVERAUS, H; PORKKA, K; GUILLHOT, J; SCHUBERT-FRITSCHLE, G; CASTAGNETTI, F; LEJNIECE, S; GRISKEVICIUS, L; THIELEN, N; HELLMANN, A; TURKINA, A; ZARITSKEY, A; BOGDANOVIC, AD; INDRAK, K, 2014:THE EUTOS POPULATION BASED REGISTRY - INCIDENCES OF CML ACROSS EUROPE. HAEMATOLOGICA 99 , p. 72 - 72.
• LENGEROVA, M; RACIL, Z; HRNCIROVA, K; KOCMANOVA, I; VOLFOVA, P; RICNA, D; BEJDAK, P; MOULIS, M; PAVLOVSKY, Z; WEINBERGEROVA, B; TOSKOVA, M; MAYER, J, 2014:Rapid Detection and Identification of Mucormycetes in Bronchoalveolar Lavage Samples from Immunocompromised Patients with Pulmonary Infiltrates by Use of High-Resolution Melt Analysis. JOURNAL OF CLINICAL MICROBIOLOGY 52 (8), p. 2824 - 2828.
• LINDOERFER, D; HOFFMANN, VS; ROSTI, G; CASTAGNETTI, F; SAUSSELE, S; GUILHOT, J; SIMONSSON, B; STEEGMANN, JL; MAYER, J; INDRAK, K; TURKINA, AG; ZARITSKEY, A; LABAR, B; ZUPAN, IP; THIELEN, N; CLARK, RE; THALER, J; MELANTHIOU, F; EVERAUS, H; PORKKA, K; BOGDA, 2014:THE EUTOS POPULATION-BASED REGISTRY: EVALUATION OF BASELINE CHARACTERISTICS AND FIRST TREATMENT CHOICES OF 2983 NEWLY DIAGNOSED CHRONIC MYELOID LEUKEMIA (CML) PATIENTS FROM 20 EUROPEAN COUNTRIES. HAEMATOLOGICA 99 , p. 238 - 239.
• NAVRKALOVA, V; MARECKOVA, A; JANIKOVA, A; DOUBEK, M; MAYER, J; POSPISILOVA, S; TRBUSEK, M, 2014:INCORPORATION OF NEXT-GENERATION SEQUENCING INTO ATM GENE ANALYSIS IN PATIENTS WITH CLL AND MCL. HAEMATOLOGICA 99 , p. 312 - 312.
• ROBESOVA, B; BAJEROVA, M; LISKOVA, K; SKRICKOVA, J; TOMISKOVA, M; POSPISILOVA, S; MAYER, J; DVORAKOVA, D, 2014:TaqMan based real time PCR assay targeting EML4-ALK fusion transcripts in NSCLC. LUNG CANCER 85 (1), p. 25 - 30.
• VERNER, J; TRBUSEK, M; CHOVANCOVA, J; SKABRAHOVA, H; JASKOVA, Z; MOULIS, M; FOLBER, F; HALOUZKA, R; MAYER, J; POSPISILOVA, S; DOUBEK, M, 2014:NOD/SCID GAMMA XENOGRAFT MODEL OF B-CELL MALIGNANCIES USING TP53-AND/OR ATM-DEFICIENT CELL LINES. HAEMATOLOGICA 99 , p. 312 - 313.

2013

• BACCARANI, M; DEININGER, MW; ROSTI, G; HOCHHAUS, A; SOVERINI, S; APPERLEY, JF; CERVANTES, F; CLARK, RE; CORTES, JE; GUILHOT, F; HJORTH-HANSEN, H; HUGHES, TP; KANTARJIAN, HM; KIM, DW; LARSON, RA; LIPTON, JH; MAHON, FX; MARTINELLI, G; MAYER, J; MULLER, MC; , 2013:European LeukemiaNet recommendations for the management of chronic myeloid leukemia: 2013. BLOOD 122 (6), p. 872 - 884.
• FINK, AM; BOTTCHER, S; RITGEN, M; FISCHER, K; PFLUG, N; EICHHORST, B; WENDTNER, CM; WINKLER, D; BUHLER, A; ZENZ, T; STAIB, P; MAYER, J; HENSEL, M; HOPFINGER, G; WENGER, M; FINGERLE-ROWSON, G; DOHNER, H; KNEBA, M; STILGENBAUER, S; BUSCH, R; HALLEK, M, 2013:Prediction of poor outcome in CLL patients following first-line treatment with fludarabine, cyclophosphamide and rituximab. LEUKEMIA 27 (9), p. 1949 - 1952.
• HOFFMANN, VS; BACCARANI, M; LINDOERFER, D; CASTAGNETTI, F; TURKINA, A; ZARITSKY, A; HELLMANN, A; PREJZNER, W; STEEGMANN, JL; MAYER, J; INDRAK, K; COLITA, A; ROSTI, G; PFIRRMANN, M, 2013:The EUTOS prognostic score: review and validation in 1288 patients with CML treated frontline with imatinib. LEUKEMIA 27 (10), p. 2016 - 2022.
• RACIL, Z; RAZGA, F; DRAPALOVA, J; BURESOVA, L; ZACKOVA, D; PALACKOVA, M; SEMERAD, L; MALASKOVA, L; HALUZIK, M; MAYER, J, 2013:Mechanism of impaired glucose metabolism during nilotinib therapy in patients with chronic myelogenous leukemia. HAEMATOLOGICA 98 (10)

2012

• JANIKOVA, A; MARECKOVA, A; DVORAKOVA, D; BORTLICEK, Z; TICHY, B; NAVRATIL, M; KRAL, Z; POSPISILOVA, S; MAYER, J, 2012:A real-time (PCR) for a real life ...? Quantitative evaluation of BCL2/IGH in follicular lymphoma and its implications for clinical practice. EXPERIMENTAL HEMATOLOGY 40 (7), p. 528 - 539.
• KOZUBIK, KS; MALCIKOVA, J; TRBUSEK, M; TOM, N; DOUBEK, M; BRYCHTOVA, Y; SMARDOVA, J; MAYER, J; POSPISILOVA, S; TICHY, B, 2012:Clonal Selection of TP53 Mutations in Chronic Lymphocytic Leukaemia Detected by Ultra-deep Pyrosequencing. EUROPEAN JOURNAL OF CANCER 48 , p. S146 - S146.
• LENGEROVA, M; KOCMANOVA, I; RACIL, Z; HRNCIROVA, K; POSPISILOVA, S; MAYER, J; NAJVAR, LK; WIEDERHOLD, NP; KIRKPATRICK, WR; PATTERSON, TF, 2012:Detection and Measurement of Fungal Burden in a Guinea Pig Model of Invasive Pulmonary Aspergillosis by Novel Quantitative Nested Real-Time PCR Compared with Galactomannan and (1,3)-beta-D-Glucan Detection. JOURNAL OF CLINICAL MICROBIOLOGY 50 (3), p. 602 - 608.
• MRAZ, M; DOLEZALOVA, D; PLEVOVA, K; KOZUBIK, KS; MAYEROVA, V; CERNA, K; MUSILOVA, K; TICHY, B; PAVLOVA, S; BORSKY, M; VERNER, J; DOUBEK, M; BRYCHTOVA, Y; TRBUSEK, M; HAMPL, A; MAYER, J; POSPISILOVA, S, 2012:MicroRNA-650 expression is influenced by immunoglobulin gene rearrangement and affects the biology of chronic lymphocytic leukemia. BLOOD 119 (9), p. 2110 - 2113.

2011

• TRBUSEK, M; SMARDOVA, J; MALCIKOVA, J; SEBEJOVA, L; DOBES, P; SVITAKOVA, M; VRANOVA, V; MRAZ, M; FRANCOVA, HS; DOUBEK, M; BRYCHTOVA, Y; KUGLIK, P; POSPISILOVA, S; MAYER, J, 2011:Missense Mutations Located in Structural p53 DNA-Binding Motifs Are Associated With Extremely Poor Survival in Chronic Lymphocytic Leukemia. JOURNAL OF CLINICAL ONCOLOGY 29 (19), p. 2703 - 2708.
• WALEWSKI, J; PASZKIEWICZ-KOZIK, E; WARSZEWSKA, A; BORSARU, G; MOICEAN, A; HELLMANN, A; MAYER, J; HAUNS, B; MAIS, A; HENNING, SW; HENTSCH, B, 2011:Final Results of the Phase II SAPHIRE Trial of Resminostat (4SC-201) in Patients with Relapsed/Refractory Hodgkin Lymphoma. BLOOD 118 (21), p. 1149 - 1149.

2010

• KOTASKOVA, JANA; TICHY, BORIS; TRBUSEK, MARTIN; FRANCOVA, HANA SKUHROVA; KABATHOVA, JITKA; MALCIKOVA, JITKA; DOUBEK, MICHAEL; BRYCHTOVA, YVONA; MAYER, JIRI; POSPISILOVA, SARKA, 2010:High Expression of Lymphocyte-Activation Gene 3 (LAG3) in Chronic Lymphocytic Leukemia Cells Is Associated with Unmutated lmmunoglobulin Variable Heavy Chain Region (IGHV) Gene and Reduced Treatment-Free Survival. JOURNAL OF MOLECULAR DIAGNOSTICS 12 (3), p. 328 - 334.
• MALCIKOVA, J; TICHY, B; DAMBORSKY, J; KABATHOVA, J; TRBUSEK, M; MAYER, J; POSPISILOVA, S, 2010:Analysis of the DNA-binding activity of p53 mutants using functional protein microarrays and its relationship to transcriptional activation. BIOLOGICAL CHEMISTRY 391 (2 III), p. 197 - 205.

2009

• MRAZ, M., MALINOVA, K., KOTASKOVA, J., PAVLOVA, S., TICHY, B., MALCIKOVA, J., STANO-KOZUBIK, K., SMARDOVA, J., BRYCHTOVA, Y., DOUBEK, M., TRBUSEK, M., MAYER, J., POSPISILOVA, S., 2009:miR-34a, miR-29c and miR-17-5p are downregulated in CLL patients with TP53 abnormalities. Leukemia 23 (6), p. 1159 - 1163.

Pracoviště 1:	Masarykova univerzita - CEITEC MU Kamenice 753/5, Brno, 625 00, kancelář bud. A17/333
Pracoviště 2:	Masarykova univerzita Kamenice 753/5, Brno, 625 00