Cryo-electron microscopy (cryo-EM) allows the three-dimensional (3D) visualization/ characterization of biological structures in a close-to-native state that range from individual macromolecular complexes and large molecular machines to the intricate macromolecular network within entire cells. While single particle methods enable us to obtain 3D structures of isolated and purified complexes to sub-nanometer resolution, cryo-electron tomography allows today studies in situ, which offers the possibility to do quantitative cell biology studies at the molecular level and even under different physiological conditions.
The combination of cryo-EM with other complementary methods of structural biology (such as NMR, X-ray crystallography and mass-spectrometry) will provide the structural basis for our future understanding of biological processes, expanding our knowledge into hitherto unknown dimensions. This symposium aims to bring together world leading scientists in the field of cryoelectron microscopy, who will present and discuss their latest research and who will give a glimpse into the future of a field that is going through a revolution in technology that represents a quantum leap which had not been seen in over two decades.
Confirmed speakers:
- Wolfgang Baumeister (MPIB Munich, DE)
- Alasdair Steven (NIH, USA)
- Christian Spahn (Charite, Berlin, DE)
- David DeRosier (Brandeis, USA)
More information at CryoEM@ceitec.cz.
Programme to download can be found HERE.
